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Power Blue (Methylene Blue) | 60mL

Power Blue (Methylene Blue) | 60mL

High-Purity Methylene Blue for Research Applications

$34.99

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Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

Overview

Power Blue or Methylene Blue (MB) is a water-soluble, synthetic phenothiazine compound with a long history of use in medicine, chemistry, and biology. Originally developed as a textile dye in the 19th century, it was later discovered to have pharmacological properties, including redox cycling, mitochondrial enhancement, neuroprotection, and antimicrobial activity.

Chemical Information

  • Chemical Formula: C₁₆H₁₈ClN₃S
  • Molecular Weight: 319.85 g/mol
  • CAS Number: 61-73-4
  • Solubility: Water-Soluble

Storage & Stability

  • Storage Temperature: Room temperature (15-25°C)
  • Shelf Life: Stable for up to three years when stored in a cool, dark place
  • Avoid Direct Light: MB is photosensitive and should be kept in an amber or opaque container to maintain potency

Key Features

  • High Purity (USP-Grade) – Ensuring top-tier research applications
  • 1% Aqueous Solution – Precisely formulated for research use
  • Redox Agent – Plays a key role in cellular respiration and ATP production
  • Neuroprotective Properties – Supports mitochondrial function and cognitive performance
  • Antimicrobial and Antiviral Effects – Used for its antibacterial, antifungal, and antiviral properties
  • Methemoglobinemia Treatment – Recognized by the FDA for reversing methemoglobinemia
  • Enhances Energy Metabolism – Supports cellular energy production via the mitochondrial electron transport chain

Mechanism of Action

Methylene Blue functions as an electron donor and acceptor, meaning it facilitates electron transport in mitochondrial respiration. It improves ATP production by bypassing Complex I & III of the electron transport chain, reducing oxidative stress and boosting energy metabolism.
Additionally, MB is a monoamine oxidase (MAO) inhibitor, which means it can influence neurotransmitter levels, particularly dopamine and serotonin, making it a potential nootropic for cognitive enhancement.

Potential Benefits

  • Mitochondrial Support & Energy Production – Enhances ATP synthesis by improving mitochondrial efficiency, making it useful for fatigue-related conditions.
  • Cognitive Function & Neuroprotection – MB has been studied for its role in Alzheimer’s, Parkinson’s, and other neurodegenerative conditions due to its ability to improve memory retention, increase blood flow to the brain, and reduce oxidative damage.
  • Anti-Aging & Longevity – As a potent antioxidant, MB neutralizes reactive oxygen species (ROS), reducing cellular damage and supporting longevity research.
  • Antimicrobial Properties – Exhibits antibacterial, antifungal, and antiviral effects. Historically used to treat urinary tract infections and malaria.
  • Mood & Mental Clarity – As an MAO inhibitor, MB has been investigated for its ability to modulate serotonin and dopamine levels, potentially improving mood, reducing depression, and enhancing focus.
  • Anti-Inflammatory Effects – MB is shown to reduce inflammation in multiple pathways, supporting overall health and cellular function.

Research Applications

  • Neurodegenerative Disease Models – Investigated for potential applications in Alzheimer’s, Parkinson’s, and traumatic brain injury.
  • Cellular Respiration Studies – Used in research to analyze mitochondrial efficiency and redox balance.
  • Antibacterial & Antiviral Research – Studied as an alternative to conventional antimicrobial agents.
  • Photodynamic Therapy – MB is used in research for its light-activated properties to treat infections and cancer cells.

Recommended Dosage & Administration

Methylene Blue is widely researched, and its dosing depends on intended use:

  • Low-Dose (Cognitive & Mitochondrial Support): 0.5 mg – 4 mg per kg body weight
  • Medium-Dose (Methemoglobinemia Treatment): 1 – 2 mg/kg intravenously
  • High-Dose (Antimicrobial Use & Research Applications): 10 mg – 50 mg per kg body weight

Methylene Blue should never be combined with SSRIs, SNRIs, or MAOIs, as it can cause serotonin syndrome, a potentially dangerous condition. Always research interactions before use.

Safety & Side Effects

Methylene Blue is well tolerated at low doses but can cause adverse effects at higher doses.

Common Side Effects:

  • Mild nausea or stomach discomfort
  • Temporary blue or green urine discoloration (normal)
  • Headaches (typically transient)

Potential Risks at Higher Doses:

  • Serotonin Syndrome: Due to MAO inhibition, MB should never be combined with SSRIs, SNRIs, or other serotonergic drugs.
  • Oxidative Stress at High Doses: While MB is an antioxidant at low doses, excessive amounts may lead to pro-oxidant effects.
  • Gastrointestinal Distress: Some users experience nausea, diarrhea, or vomiting at higher doses.

Frequently Asked Questions

What is Methylene Blue used for in research?

It is commonly used for studying mitochondrial function, cognitive enhancement, antimicrobial effects, and cellular respiration.

Can Methylene Blue improve cognitive function?

Yes, MB has been shown to enhance memory, attention, and cognitive processing speed in both animal and human studies.

Is Methylene Blue safe?

At low doses, MB is generally safe, but it should not be mixed with serotonergic medications.

Does Methylene Blue stain teeth or skin?

It can temporarily stain tissues, but it is water-soluble and can be rinsed off easily.

Can Methylene Blue be used for photodynamic therapy?

Yes, MB is used in research involving light-activated antimicrobial and anticancer applications.

For Research Purposes Only

Methylene Blue is sold strictly for laboratory and research use. It is not intended for human consumption or medical treatment.

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For Research Use Only – Not for Human or Veterinary Consumption

Important legal Notice:

All products sold and distributed by PeptidePro.io are intended solely for legitimate laboratory research and development purposes. These products are not to be used for any other purposes, including but not limited to: 

  • In vivo or in vitro diagnostic use
  • Therapeutic applications
  • Human or animal consumption
  • Food or drug use
  • Cosmetic, agricultural, or household applications
FDA Disclosure:

None of the products provided by PeptidePro.io have been approved, cleared, or authorized by the U.S. Food and Drug Administration (FDA) for any use, whether experimental or clinical. These compounds are not classified as drugs, supplements, food additives, or medical devices, and it is a violation of federal law to use these materials in humans or animals.

Intended Users:

By purchasing from PeptidePro.io, the purchaser certifies that they are:

  1. A qualified researcher, laboratory technician, institution, or entity with the appropriate knowledge and facilities to handle potentially hazardous research materials.
  2. In compliance with all federal, state, and local laws regarding the use, possession, handling, and disposal of research chemicals.
  3. Aware that misuse, diversion, or mishandling of these materials may result in serious legal consequences, health hazards, and civil or criminal liability.
Assumption Of Risk & Liability Waiver:

The purchaser acknowledges and assumes all risk associated with the purchase, handling, storage, and use of any product sold by PeptidePro.io. By purchasing, you agree to:

  • Waive all claims against PeptidePro.io, its owners, employees, agents, and affiliates, for any loss, injury, or damage arising from use or misuse of products.
  • Indemnify and hold harmless PeptidePro.io from all claims, liabilities, and expenses (including attorney's fees) arising from purchaser's use or resale of any product in violation of this agreement or applicable law.
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PeptidePro.io makes no representations or warranties, express or implied, regarding the merchantability, fitness for a particular purpose, or safety of any product. All products are sold “as-is” and “with all faults.”

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PeptidePro.io reserves the right to deny sale or service to any person or entity suspected of misuse, illegal intent, or unethical practices. All transactions are monitored for compliance with this policy.

By Placing An Order With Peptidepro.io, You Agree To Be Bound By The Terms Of This Disclosure In Full.

If you do not agree, do not complete a purchase or use the site.

All products sold and distributed by PeptidePro.io are intended solely for legitimate laboratory research and development purposes. These products are not to be used for any other purposes, including but not limited to: 

  • - In vivo or in vitro diagnostic use
  • - Therapeutic applications
  • - Human or animal consumption
  • - Food or drug use
  • - Cosmetic, agricultural, or household applications

None of the products provided by PeptidePro.io have been approved, cleared, or authorized by the U.S. Food and Drug Administration (FDA) for any use, whether experimental or clinical. These compounds are not classified as drugs, supplements, food additives, or medical devices, and it is a violation of federal law to use these materials in humans or animals.

By purchasing from PeptidePro.io, the purchaser certifies that they are:

  1. A qualified researcher, laboratory technician, institution, or entity with the appropriate knowledge and facilities to handle potentially hazardous research materials.
  2. In compliance with all federal, state, and local laws regarding the use, possession, handling, and disposal of research chemicals.
  3. Aware that misuse, diversion, or mishandling of these materials may result in serious legal consequences, health hazards, and civil or criminal liability.

The purchaser acknowledges and assumes all risk associated with the purchase, handling, storage, and use of any product sold by PeptidePro.io. By purchasing, you agree to:

  • - Waive all claims against PeptidePro.io, its owners, employees, agents, and affiliates, for any loss, injury, or damage arising from use or misuse of products.
  • - Indemnify and hold harmless PeptidePro.io from all claims, liabilities, and expenses (including attorney's fees) arising from purchaser's use or resale of any product in violation of this agreement or applicable law.

PeptidePro.io makes no representations or warranties, express or implied, regarding the merchantability, fitness for a particular purpose, or safety of any product. All products are sold "as-is" and "with all faults."

PeptidePro.io reserves the right to deny sale or service to any person or entity suspected of misuse, illegal intent, or unethical practices. All transactions are monitored for compliance with this policy.

If you do not agree, do not complete a purchase or use the site.

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